Products Description of Amoxicillin CAS#26787-78-0
Amoxicillin, alternatively referred to as anmercillin, is a classic broad-spectrum beta-lactam antibiotic belonging to the penicillin family. The product presents as a white powdered solid with a biological half-life of roughly 61.3 minutes. Featuring excellent acid stability, it achieves a gastrointestinal absorption rate as high as 90% after oral administration.
As a semi-synthetic penicillin antibiotic, it possesses potent bactericidal properties and superior cell membrane permeability, supporting extensive clinical application. It is commercially available in multiple dosage forms, including capsules, granules, tablets and injections. For injectable formulations, amoxicillin is frequently compounded with clavulanic acid or sulbactam to optimize its medicinal efficacy.
This antibiotic is primarily applied for the clinical treatment of upper and lower respiratory tract infections, otitis media, sinusitis, acute urethritis and various other severe inflammatory diseases. Benefiting from its broad antimicrobial coverage, rapid pharmacological action and high oral absorption efficiency, amoxicillin serves as a highly effective therapeutic antibiotic in clinical medicine.
Amoxicillin Chemical Properties
| Melting point | 140 °C |
| Boiling point | 743.2±60.0 °C(Predicted) |
| density | 1.54±0.1 g/cm3(Predicted) |
| vapor pressure | 0Pa at 25℃ |
| storage temp. | 2-8°C |
| pka | pKa 2.4 (Uncertain) |
| form | solid |
| color | White to off-white |
| Water Solubility | 4g/L at 25℃ |
| Merck | 13582 |
| BRN | 7507120 |
| BCS Class | 1,3 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | LSQZJLSUYDQPKJ-UWFZAAFLSA-N |
| LogP | 0.87 at 25℃ |
| CAS DataBase Reference | 26787-78-0(CAS DataBase Reference) |
| EPA Substance Registry System | 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)- (26787-78-0) |
| Hazard Codes | Xn,Xi |
| Risk Statements | 42/43 |
| Safety Statements | 22-36/37 |
| WGK Germany | 2 |
| RTECS | XH8300000 |
| HS Code | 29411000 |
| Hazardous Substances Data | 26787-78-0(Hazardous Substances Data) |
Product Application of Amoxicillin CAS#26787-78-0
Amoxicillin is a mainstream antibacterial and anti-inflammatory pharmaceutical reagent with reliable and stable therapeutic effects, ranking as a common essential household medicine. It features outstanding oral absorption performance; under equivalent dosage conditions, its serum drug concentration is nearly twice that of ampicillin.
This antibiotic is extensively prescribed for infections of the respiratory system, urinary system and biliary system, as well as typhoid fever induced by susceptible bacteria. Its major clinical anti-infective applications are categorized as follows:
Upper and lower respiratory tract infections: applicable for otitis media, sinusitis, pharyngitis, tonsillitis, acute bronchitis and pneumonia caused by susceptible pathogens.
Skin and soft tissue infections: capable of treating a wide range of bacterial infections occurring in human skin and soft tissues.
Urinary and reproductive tract infections: commonly used for acute bacterial nephritis, acute cystitis, acute urethritis and simple acute gonorrhea.
Helicobacter pylori eradication treatment: combined with metronidazole and omeprazole, it can effectively remove Helicobacter pylori colonies in gastric and duodenal lesions, lowering the recurrence rate of peptic ulcers.
